Metabolic adaptation underlies epigenetic reprogramming in chemotherapy resistant breast cancer
Curie Institute 26 rue d'Ulm, Paris, FranceMathieu Lupien (Department of Medical Biophysics, University of Toronto) Mercredi 19 juin à 11h30, amphithéâtre Antoine Lacassagne, Centre de Recherche de Paris Cancer cell survival upon cytotoxic drug exposure leads to changes in cell identity which is directly regulated by the epigenome. Several metabolites serve as substrates or co-factors to chromatin-modifying enzymes, suggesting that metabolic…
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