Computational analysis of liver cancer genomes reveals new mutational signatures and drivers events
Curie Institute 26 rue d'Ulm, Paris, FranceEric Letouzé (Centre de Recherche des Cordeliers) Genomic alterations driving tumorigenesis result from endogenous cellular processes and environmental exposures. Each mutational process leaves a characteristic imprint – a mutational signature – on the genome in the form of preferential types of mutation occurring in specific sequence contexts. We have developed innovative computational tools to explore…
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