T3S-1124 - UMR-S 1124
Université de Paris
Campus Saint-Germain-des-Près
45 rue des Saints Pères
75270 Paris Cedex 06

Fax : +33 (0) 1 42 86 38 68

Mathéa Pietri

Associate professor, MCU Paris Descartes
Stem cells, Signaling and prions

mathea.pietri@-Code to remove to avoid SPAM-u-paris.fr
+33 1 42 86 20 67, room R287

Education

2002-2006       PhD in Biochemistry– ED « Signalisations, Neurosciences, Endocrinologie et Reproduction» -ParisXI.

1995-1999      Ecole Normale Supérieure, Cachan

Maîtrise (BSc) in Biochemistry – Paris VII

Agrégation de Sciences de la Vie et de la Terre – ENS Ulm/ Paris XI.

DEA (MSc) in “Génie Enzymatique, Bioconversion et Microbiologie” – UTC

Current Position

2012-…           Associate Professor of Biochemistry- Paris Descartes University (Paris V).

2009-…           Educational Manager of the international Master 1 BioMedical Engineering

  (BME- Paris Descartes University/ ParisTech – http://www.bme-paris.com/)

Selected publications

• Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation.
  Alleaume-Butaux A, Nicot S, Pietri M, Baudry A, Dakowski C, Tixador P, Ardila-Osorio H, Haeberlé AM, Bailly Y, Peyrin JM, Launay JM, Kellermann O, Schneider B : PLoS Pathog, 2015
• PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer\\’s diseases.
  Pietri M, Dakowski C, Hannaoui S, Alleaume-Butaux A, Hernandez-Rapp J, Ragagnin A, Mouillet-Richard S, Haik S, Bailly Y, Peyrin JM, Launay JM, Kellermann O, Schneider B : Nat Med, 2013
• Neuritogenesis: the prion protein controls β1 integrin signaling activity.
  Loubet D, Dakowski C, Pietri M, Pradines E, Bernard S, Callebert J, Ardila-Osorio H, Mouillet-Richard S, Launay JM, Kellermann O, Schneider B : FASEB J, 2011
• Overstimulation of PrPC signaling pathways by prion peptide 106-126 causes oxidative injury of bioaminergic neuronal cells.
  Pietri M, Caprini A, Mouillet-Richard S, Pradines E, Ermonval M, Grassi J, Kellermann O, Schneider B : J Biol Chem, 2006
• Reactive oxygen species-dependent TNF-alpha converting enzyme activation through stimulation of 5-HT2B and alpha1D autoreceptors in neuronal cells.
  Pietri M, Schneider B, Mouillet-Richard S, Ermonval M, Mutel V, Launay JM, Kellermann O : FASEB J, 2005